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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GOSR2 All Species: 27.58
Human Site: S129 Identified Species: 50.56
UniProt: O14653 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14653 NP_001012529.1 212 24775 S129 E S L Q F N S S L Q K V H N G
Chimpanzee Pan troglodytes XP_001135292 212 24759 S129 E S L Q F N S S L Q K V H N G
Rhesus Macaque Macaca mulatta XP_001115716 212 24826 S129 E S L Q F N S S L Q K V H H G
Dog Lupus familis XP_853038 212 24608 S129 D S L Q F N S S L Q K I H H G
Cat Felis silvestris
Mouse Mus musculus O35166 212 24707 S129 E S L Q F N S S L H N I H H G
Rat Rattus norvegicus O35165 212 24589 S129 E S L Q F N S S L Q N I H H G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001074333 140 16958 K67 P N K R Q N A K L R V D Q L K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_955982 212 24551 S129 E T L Q F N S S L Q N A H R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRL2 216 24815 H129 Q L D Y E L Q H H T Q L G N A
Honey Bee Apis mellifera XP_396365 212 24355 L130 N V Q H N Y S L K N A I Y G V
Nematode Worm Caenorhab. elegans P41941 213 24632 L130 E L L L N D R L Q S S H T H L
Sea Urchin Strong. purpuratus XP_794856 214 24852 S131 H E L Q H N T S L H N S H R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SJL6 225 25610 V143 E A Q A M S S V K N S K R M L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 97.1 90 N.A. 88.2 91 N.A. N.A. 49.5 N.A. 75.4 N.A. 40.7 49 32.3 50.4
Protein Similarity: 100 100 99 96.2 N.A. 93.8 96.2 N.A. N.A. 58.4 N.A. 89.6 N.A. 62.9 69.8 55.4 69.1
P-Site Identity: 100 100 93.3 80 N.A. 73.3 80 N.A. N.A. 13.3 N.A. 73.3 N.A. 6.6 6.6 13.3 40
P-Site Similarity: 100 100 100 100 N.A. 86.6 93.3 N.A. N.A. 40 N.A. 80 N.A. 26.6 20 26.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 8 0 0 0 8 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 0 8 0 0 0 0 0 8 0 0 0 % D
% Glu: 62 8 0 0 8 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 54 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 54 % G
% His: 8 0 0 8 8 0 0 8 8 16 0 8 62 39 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 31 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 8 16 0 31 8 0 0 8 % K
% Leu: 0 16 70 8 0 8 0 16 70 0 0 8 0 8 16 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 8 8 0 0 16 70 0 0 0 16 31 0 0 24 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 16 62 8 0 8 0 8 47 8 0 8 0 0 % Q
% Arg: 0 0 0 8 0 0 8 0 0 8 0 0 8 16 0 % R
% Ser: 0 47 0 0 0 8 70 62 0 8 16 8 0 0 0 % S
% Thr: 0 8 0 0 0 0 8 0 0 8 0 0 8 0 0 % T
% Val: 0 8 0 0 0 0 0 8 0 0 8 24 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 8 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _